Middle East Journal of Rehabilitation and Health

Published by: Kowsar

Does Continuous Extremely Low-Frequency Electromagnetic Fields Exposure Harms Liver Tissue? A Microscopic Assay

Vahid Semnani 1 , Hadi Hasanzadeh 2 , 3 , * , Amir Darbandi-Azar 4 , Samaneh Seyyedi 5 , Alireza Emadi 6 and Mostafa Rezaei-Tavirani 7
Authors Information
1 Clinical Research Development Unit (CRDU), Kowsar hospital, Semnan University of Medical Sciences, Semnan, Iran
2 Cancer Research Center, Semnan University of Medical Sciences, Semnan, Iran
3 Department of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran
4 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
5 Aramesh molecular and genetic diagnostic laboratory, Department of Genetics, Tehran, Iran
6 Deputy of Research and Technology, Semnan University of Medical Sciences, Semnan, Iran
7 Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Article information
  • Middle East Journal of Rehabilitation and Health: January 2018, 5 (1); e63105
  • Published Online: January 28, 2018
  • Article Type: Research Article
  • Received: October 21, 2017
  • Revised: December 27, 2017
  • Accepted: January 14, 2018
  • DOI: 10.5812/mejrh.63105

To Cite: Semnani V, Hasanzadeh H, Darbandi-Azar A, Seyyedi S, Emadi A, et al. Does Continuous Extremely Low-Frequency Electromagnetic Fields Exposure Harms Liver Tissue? A Microscopic Assay, Middle East J Rehabil Health Stud. 2018 ; 5(1):e63105. doi: 10.5812/mejrh.63105.

Abstract
Copyright © 2018, Middle East Journal of Rehabilitation and Health Studies. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
Acknowledgements
References
  • 1. Grellier J, Ravazzani P, Cardis E. Potential health impacts of residential exposures to extremely low frequency magnetic fields in Europe. Environ Int. 2014;62:55-63. doi: 10.1016/j.envint.2013.09.017. [PubMed: 24161447].
  • 2. Ivancsits S, Diem E, Pilger A, Rudiger HW, Jahn O. Induction of DNA strand breaks by intermittent exposure to extremely-low-frequency electromagnetic fields in human diploid fibroblasts. Mutat Res. 2002;519(1-2):1-13. doi: 10.1016/S1383-5718(02)00109-2. [PubMed: 12160887].
  • 3. Karasek M, Woldanska-Okonska M. Electromagnetic fields and human endocrine system. ScientificWorldJournal. 2004;4 Suppl 2:23-8. doi: 10.1100/tsw.2004.175. [PubMed: 15517099].
  • 4. Hasanzadeh H, Rezaei-Tavirani M, Seyyedi SS, Zali H, Heydari Keshel S, Jadidi M, et al. Effect of ELF-EMF Exposure on Human Neuroblastoma Cell Line: a Proteomics Analysis. Iran J Cancer Prev. 2014;7(1):22-7. [PubMed: 25250144].
  • 5. Rezaei-Tavirani M, Hasanzadeh H, Seyyedi S, Zali H. Proteomic Analysis of the Effect of Extremely Low-Frequency Electromagnetic Fields (ELF-EMF) With Different Intensities in SH-SY5Y Neuroblastoma Cell Line. J Lasers Med Sci. 2017;8(2):79-83. doi: 10.15171/jlms.2017.14. [PubMed: 28652900].
  • 6. Rostami A, Shahani M, Zarrindast MR, Semnanian S, Rahmati Roudsari M, Rezaei Tavirani M, et al. Effects of 3 Hz and 60 Hz Extremely Low Frequency Electromagnetic Fields on Anxiety-Like Behaviors, Memory Retention of Passive Avoidance and Electrophysiological Properties of Male Rats. J Lasers Med Sci. 2016;7(2):120-5. doi: 10.15171/jlms.2016.20. [PubMed: 27330708].
  • 7. Safari M, Jadidi M, Baghian A, Hasanzadeh H. Proliferation and differentiation of rat bone marrow stem cells by 400muT electromagnetic field. Neurosci Lett. 2016;612:1-6. doi: 10.1016/j.neulet.2015.11.044. [PubMed: 26639423].
  • 8. Cuccurazzu B, Leone L, Podda MV, Piacentini R, Riccardi E, Ripoli C, et al. Exposure to extremely low-frequency (50 Hz) electromagnetic fields enhances adult hippocampal neurogenesis in C57BL/6 mice. Exp Neurol. 2010;226(1):173-82. doi: 10.1016/j.expneurol.2010.08.022. [PubMed: 20816824].
  • 9. Kheifets L, Ahlbom A, Crespi CM, Draper G, Hagihara J, Lowenthal RM, et al. Pooled analysis of recent studies on magnetic fields and childhood leukaemia. Br J Cancer. 2010;103(7):1128-35. doi: 10.1038/sj.bjc.6605838. [PubMed: 20877339].
  • 10. Schuz J. Exposure to extremely low-frequency magnetic fields and the risk of childhood cancer: update of the epidemiological evidence. Prog Biophys Mol Biol. 2011;107(3):339-42. doi: 10.1016/j.pbiomolbio.2011.09.008. [PubMed: 21946043].
  • 11. Zaryabova V, Shalamanova T, Israel M. Pilot study of extremely low frequency magnetic fields emitted by transformers in dwellings. Social aspects. Electromagn Biol Med. 2013;32(2):209-17. doi: 10.3109/15368378.2013.776431. [PubMed: 23675624].
  • 12. Wolf FI, Torsello A, Tedesco B, Fasanella S, Boninsegna A, D'Ascenzo M, et al. 50-Hz extremely low frequency electromagnetic fields enhance cell proliferation and DNA damage: possible involvement of a redox mechanism. Biochim Biophys Acta. 2005;1743(1-2):120-9. doi: 10.1016/j.bbamcr.2004.09.005. [PubMed: 15777847].
  • 13. Falone S, Grossi MR, Cinque B, D'Angelo B, Tettamanti E, Cimini A, et al. Fifty hertz extremely low-frequency electromagnetic field causes changes in redox and differentiative status in neuroblastoma cells. Int J Biochem Cell Biol. 2007;39(11):2093-106. doi: 10.1016/j.biocel.2007.06.001. [PubMed: 17662640].
  • 14. Ruiz Gomez MJ, De la Pena L, Pastor JM, Martinez Morillo M, Gil L. 25 Hz electromagnetic field exposure has no effect on cell cycle distribution and apoptosis in U-937 and HCA-2/1cch cells. Bioelectrochemistry. 2001;53(1):137-40. doi: 10.1016/S0302-4598(00)00119-7. [PubMed: 11206921].
  • 15. Piacentini R, Ripoli C, Mezzogori D, Azzena GB, Grassi C. Extremely low-frequency electromagnetic fields promote in vitro neurogenesis via upregulation of Ca(v)1-channel activity. J Cell Physiol. 2008;215(1):129-39. doi: 10.1002/jcp.21293. [PubMed: 17941084].
  • 16. Singh N, Lai H. 60 Hz magnetic field exposure induces DNA crosslinks in rat brain cells. Mutat Res. 1998;400(1-2):313-20. doi: 10.1016/S0027-5107(98)00017-7. [PubMed: 9685689].
  • 17. Winker R, Ivancsits S, Pilger A, Adlkofer F, Rudiger HW. Chromosomal damage in human diploid fibroblasts by intermittent exposure to extremely low-frequency electromagnetic fields. Mutat Res. 2005;585(1-2):43-9. doi: 10.1016/j.mrgentox.2005.04.013. [PubMed: 16009595].
  • 18. Reale M, Kamal MA, Patruno A, Costantini E, D'Angelo C, Pesce M, et al. Neuronal cellular responses to extremely low frequency electromagnetic field exposure: implications regarding oxidative stress and neurodegeneration. PLoS One. 2014;9(8). e104973. doi: 10.1371/journal.pone.0104973. [PubMed: 25127118].
  • 19. Seyyedi SS, Dadras MS, Tavirani MR, Mozdarani H, Toossi P, Zali AR. Proteomic analysis in human fibroblasts by continuous exposure to extremely low-frequency electromagnetic fields. Pak J Biol Sci. 2007;10(22):4108-12. [PubMed: 19090288].
  • 20. Griffin GD, Khalaf W, Hayden KE, Miller EJ, Dowray VR, Creekmore AL, et al. Power frequency magnetic field exposure and gap junctional communication in Clone 9 cells. Bioelectrochemistry. 2000;51(2):117-23. doi: 10.1016/S0302-4598(99)00085-9. [PubMed: 10910159].
  • 21. Vianale G, Reale M, Amerio P, Stefanachi M, Di Luzio S, Muraro R. Extremely low frequency electromagnetic field enhances human keratinocyte cell growth and decreases proinflammatory chemokine production. Br J Dermatol. 2008;158(6):1189-96. doi: 10.1111/j.1365-2133.2008.08540.x. [PubMed: 18410412].
  • 22. Qi G, Zuo X, Zhou L, Aoki E, Okamula A, Watanebe M, et al. Effects of extremely low-frequency electromagnetic fields (ELF-EMF) exposure on B6C3F1 mice. Environ Health Prev Med. 2015;20(4):287-93. doi: 10.1007/s12199-015-0463-5. [PubMed: 25939981].
  • 23. Wen J, Jiang S, Chen Z, Zhao W, Yi Y, Yang R, et al. Apoptosis selectively induced in BEL-7402 cells by folic acid-modified magnetic nanoparticles combined with 100 Hz magnetic field. Int J Nanomedicine. 2014;9:2043-50. doi: 10.2147/IJN.S60457. [PubMed: 24790442].
  • 24. Duan Y, Wang Z, Zhang H, He Y, Lu R, Zhang R, et al. The preventive effect of lotus seedpod procyanidins on cognitive impairment and oxidative damage induced by extremely low frequency electromagnetic field exposure. Food Funct. 2013;4(8):1252-62. doi: 10.1039/c3fo60116a. [PubMed: 23764910].
  • 25. Rosai J. Rosai and Ackerman's Surgical Pathology E-Book. Elsevier Health Sciences; 2011.
  • 26. International Commission on Non-Ionizing Radiation P. Guidelines for limiting exposure to time-varying electric and magnetic fields (1 Hz to 100 kHz). Health Phys. 2010;99(6):818-36. doi: 10.1097/HP.0b013e3181f06c86. [PubMed: 21068601].
  • 27. Canseven AG, Coskun S, Seyhan N. Effects of various extremely low frequency magnetic fields on the free radical processes, natural antioxidant system and respiratory burst system activities in the heart and liver tissues. Indian J Biochem Biophys. 2008;45(5):326-31. [PubMed: 19069844].
  • 28. Emre M, Cetiner S, Zencir S, Unlukurt I, Kahraman I, Topcu Z. Oxidative stress and apoptosis in relation to exposure to magnetic field. Cell Biochem Biophys. 2011;59(2):71-7. doi: 10.1007/s12013-010-9113-0. [PubMed: 20824388].
  • 29. Hashish AH, El-Missiry MA, Abdelkader HI, Abou-Saleh RH. Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice. Ecotoxicol Environ Saf. 2008;71(3):895-902. doi: 10.1016/j.ecoenv.2007.10.002. [PubMed: 17996303].
  • 30. Jian W, Wei Z, Zhiqiang C, Zheng F. X-ray-induced apoptosis of BEL-7402 cell line enhanced by extremely low frequency electromagnetic field in vitro. Bioelectromagnetics. 2009;30(2):163-5. doi: 10.1002/bem.20461. [PubMed: 19051321].
  • 31. Liu Y, Weng E, Zhang Y, Hong R. [Effects of extremely low frequency electromagnetic field and its combination with lead on the antioxidant system in mouse]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2002;20(4):263-5. [PubMed: 14694649].
  • 32. Martinez-Samano J, Torres-Duran PV, Juarez-Oropeza MA, Elias-Vinas D, Verdugo-Diaz L. Effects of acute electromagnetic field exposure and movement restraint on antioxidant system in liver, heart, kidney and plasma of Wistar rats: a preliminary report. Int J Radiat Biol. 2010;86(12):1088-94. doi: 10.3109/09553002.2010.501841. [PubMed: 20701462].
  • 33. Zecca L, Mantegazza C, Margonato V, Cerretelli P, Caniatti M, Piva F, et al. Biological effects of prolonged exposure to ELF electromagnetic fields in rats: III. 50 Hz electromagnetic fields. Bioelectromagnetics. 1998;19(1):57-66. doi: 10.1002/(SICI)1521-186X(1998)19:1<57::AID-BEM7>3.0.CO;2-3. [PubMed: 9453708].
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